Importantly, these receptors were found to have been activated by a variety of endogenous opioids in a concentration comparable to that noticed for activation and signaling of classical opiate receptors. Subsequently, these receptors were observed to own scavenging activity, binding to and reducing endogenous levels of opiates accessible for bindin

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Importantly, these receptors have been found to are activated by a wide range of endogenous opioids at a concentration much like that noticed for activation and signaling of classical opiate receptors. Consequently, these receptors were located to have scavenging exercise, binding to and lowering endogenous levels of opiates accessible for binding